Sold under the brand name of the canagliflozin, Invokana is prescribed as an oral diabetes medicine to treat adults with type 2 diabetes mellitus. The drug is classified as a sodium-glucose co-transporter 2 (SGLT2) and is responsible to maintain the insulin level in the blood. It avoids the re-absorption of glucose in the kidneys and helps to get rid of the extra glucose through urine.
Unfortunately, the medication can cause kidney problems, vision loss, and heart issues. The common invokana side effects include but not limited to:
- Bladder infection
- Urinary infection
- Diabetic foot and leg amputation
- Diabetic nerve problem
- Blood circulation issues
One of the most serious side effects of Invokana is diabetic ketoacidosis which is a condition where there are too many ketones (acid) present in the circulating blood. It can lead to life-threatening complications if the condition is not diagnosed or treated in time. Change in breathing pattern, frequent urination (polyuria), state of confusion, frequent sense of unconsciousness and poor appetite are some of the common symptoms of ketoacidosis.
Prolonged use of Invokana causes hypotension where the blood pressure of the patient goes below the normal rate. Dehydration, bleeding, adrenal insufficiency, heart disease, infections are the common symptoms of this condition. Sometimes, non-neurologic conditions can also arise due to hypotension.
Adults, especially older people might face the loss of bone density with prolonged use of Canagliflozin. Lifestyle habits such as weight-bearing exercises, avoiding smoking, limiting alcohol and eating balanced diets can help achieve the required calcium and vitamin D level in the body. Taking supplements for micro-elements is often prescribed for such patients.
People with diabetes have about 30 times higher amputation rate than for people without diabetes. Diabetic foot ulcers, lower limb infections, gangrene, and ischemia are precipitating effects of Invokana that can lead to foot and leg amputation.